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We recently read with interest the systematic review and meta-analysis by Flynn et al,1 which aimed to “compare the effectiveness of connector decontamination with 70% alcohol wipes, alcoholic chlorhexidine gluconate wipes, or alcohol impregnated caps to prevent catheter-associated bloodstream infection (CABSI)” Aho Glélé et al (2019).

Abstract:

We recently read with interest the systematic review and meta-analysis by Flynn et al,1 which aimed to “compare the effectiveness of connector decontamination with 70% alcohol wipes, alcoholic chlorhexidine gluconate wipes, or alcohol impregnated caps to prevent catheter-associated bloodstream infection (CABSI).” The article concludes that “alcohol impregnated caps and alcoholic chlorhexidine gluconate wipes were associated with significantly less CABSI than 70% alcohol wipes,” and that these results require confirmation in randomly assigned controlled trials.

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Reference:

Aho Glélé, L.S., Guilloteau, A., Astruc, K., Carre, Y., Chaize, P., Keita-Perse, O., Lurton, Y. and Lepelletier, D. (2019) “Methods for microbial needleless connector decontamination: A systematic review and meta-analysis” – Interpret results with caution. American Journal of Infection Control. August 17th. DOI: https://doi.org/10.1016/j.ajic.2019.06.030. [epub ahead of print].