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"Our study revealed an association between insertion site inflammation (ISI) and the development of central-line-associated bloodstream infections (CLABSIs)" Kobayashi et al (2020).

Abstract:

There are currently no guidelines for central-line insertion site evaluation. Our study revealed an association between insertion site inflammation (ISI) and the development of central-line-associated bloodstream infections (CLABSIs). Automated surveillance for ISI is feasible and could help prevent CLABSI.

Reference:

Kobayashi T, Clore GS, Kukla ME, Alzunitan M, Kritzman J, Abosi O, Puig-Asensio M, Marra AR, Diekema DJ, Edmond MB, Salinas JL. Insertion site inflammation was associated with central-line-associated bloodstream infections at a tertiary-care center, 2015-2018. Infect Control Hosp Epidemiol. 2020 Oct 9:1-3. doi: 10.1017/ice.2020.445. Epub ahead of print. PMID: 33032671.