Intravenous administration of antibiotics in pediatrics
Extract:
“Prolonged and continuous perfusion of antibiotics presents multiple sources of potential interest, including optimized pharmacokinetic and pharmacodynamic parameters and reduced care load, with fewer surgical and nursing interventions. These modalities of administration are supported by considerable scientific literature, especially in intensive care patients and for severe infections (osteoarticular infections, endocarditis).”
Reference:Ourghanlian C, Caséris M, d’Huart E, Cohen R, Diamantis S. Intravenous administration of antibiotics by prolonged and continuous perfusion in a pediatric context. Infect Dis Now. 2025 Apr 27:105077. doi: 10.1016/j.idnow.2025.105077. Epub ahead of print. PMID: 40300701.