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"Whole genome sequencing (WGS) and clinical review were used to characterize 14 cases of central line-associated bloodstream infection (CLABSI) due to Staphylococcus epidermidis" Zhou et al (2025).
Whole genome sequencing to characterize CLABSI

Abstract:

Whole genome sequencing (WGS) and clinical review were used to characterize 14 cases of central line-associated bloodstream infection (CLABSI) due to Staphylococcus epidermidis. WGS, which demonstrated disparate strains, suggested that 42.9% of S. epidermidis CLABSI cases were due to contamination, while clinical review suggested that 57.1% were contamination events.

Reference:

Zhou C, Wiley M, Wiley J, Cawcutt K, Grashorn E, Rogers K, McCutchen E, Iwen P, Fey P, Rupp M. Utilizing whole genome sequencing to characterize central line-associated bloodstream infections due to Staphylococcus epidermidis. Infect Control Hosp Epidemiol. 2025 Jan 27:1-4. doi: 10.1017/ice.2024.240. Epub ahead of print. PMID: 39865766.

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