Taurolidine IV lock reduces recurrent CRBSI – Full Text
“This study demonstrates that the use of 1.35% taurolidine significantly reduces the rate of recurrent CRBSIs and CVC removals due to CRBSIs compared to 0.9% saline in adult patients with CIF reliant on HPS” Nerstrøm et al (2025).
Digitalised measures for CLABSI prevention compliance – Full Text
“Digitalised interventions for CLABSI prevention seem to be effective in reducing infection rates, likely because of increasing compliance to established guidelines for CLABSI prevention” Obama et al (2025).
Peripheral venous blood gas analysis Cochrane review – Full Text
“The primary objective of this review is to evaluate the performance of PVBGA by comparing it with the reference standard ABGA, which is assumed to be error-free for the diagnosis of (1) respiratory failure, (2) hypercarbia, and (3) metabolic disturbance (the three target conditions) in adults” Byrne et al (2025).
Blood culture contamination creep – Full Text
“In a low-COVID-19-burden secondary care teaching hospital setting, blood culture contamination rates have progressively increased over the past decade, irrespective of the pandemic. These findings underscore the importance of sustained vigilance in infection prevention and control practices, strict adherence to blood culture collection protocols, and the ongoing need for staff training” Jeverica et al (2025).
OPAT for patients with substance use disorder – Full Text
“Outpatient parenteral antimicrobial therapy (OPAT) is often withheld from individuals with substance use disorder (SUD), despite evidence suggesting similar outcomes. We investigated this using a large, nationwide claims database” Rogers et al (2025).
Prevention of central line infection among ICU nurses
“The educational intervention effectively improved ICU nurses’ knowledge regarding CLABSI prevention but did not significantly change their attitudes. Tailoring interventions to demographic characteristics may further enhance their effectiveness and contribute to better patient outcomes and healthcare quality” Alzoubi et al (2025).
Patient empowerment and CLABSI reduction
“To evaluate the impact of patient empowerment in reducing the incidence density (ID) of CLABSI” Reghini et al (2025).
Review of blood culture single-sampling strategy and initial specimen diversion – Full Text
“After combined implementation of SSS and initial specimen diversion (ISDT) in our region, we evaluated the proportion of sampling events with at least four bottles, with growth of relevant pathogens and with growth of coagulase-negative staphylococci (CoNS) before and after the intervention” Oldberg et al (2025).
Simulation for central venous catheterization training
“We hypothesized that resident physicians would prefer a simulation model with high functional task alignment over a model with higher superficial resemblance and lower functional task alignment in central venous catheter placement training” Gomaa et al (2025).
Management of a positive blood cultures
“There is considerable practice variation among ED physicians for the management of positive blood cultures in children across Canada. Incongruencies in the perceived impact of clinical factors on the likelihood of a true bacteremia, such as time-to-positivity, highlight the need for a standardized decision-making tool” Gouin et al (2025).
Technique for TIVAD implantation for chemotherapy
“This bicentric, retrospective study aims to compare the surgical vein cut-down approach with ultrasound-guided percutaneous vein puncture in terms of procedural success, complication rates, and operative efficiency” Fassari et al (2025).
The Irish national OPAT programme
“The study underscores the importance of national registries in monitoring and improving OPAT services and calls for integration of microbiological data to enhance stewardship” Reidy et al (2025).
Implantable port catheter detachment – Full Text
“The chest port was placed 10 months prior without complication. An initial fluoroscopic image of the chest revealed detachment and migration of the catheter towards the right atrium. The catheter was successfully retrieved with a gooseneck snare using an inferior approach through the femoral vein” Van Vorst et al (2025).
Central line placement in newborns
“Based on this initial experience, we conclude that ultrasound-guided innominate vein cannulation is feasible and safe for infants under 4.5 kg” D’ Alessandro et al (2025).
Venous blood collection guidelines
“The guideline includes practical tools, such as checklists and detailed information on sampling devices, to facilitate implementation. This initiative would help standardize blood collection practices, improve specimen quality, and enhance patient care by ensuring accurate laboratory results in clinical settings” Chang et al (2025).
Cardiac tamponade caused by misplaced PICC – Full Text
“To prevent fatal complications such as cardiac tamponade, PICCs should be positioned in safe area. Proper placement in the superior vena cava should be confirmed and maintained” Shin et al (2025).
Subcutaneous fluid administration in pediatric sepsis – Full Text
“In this case report, we describe a seven-week-old male infant with dehydration secondary to Escherichia coli pyelonephritis. After multiple failed IV attempts, even under general anesthesia, hypodermoclysis was performed” Taha et al (2025).
PICC tip malposition case study – Full Text
“We describe 2 unusual peripherally inserted central catheter (PICC) malpositions in the left thymic vein and the right middle thyroid vein, which are, to our knowledge, the first 2 cases of PICC malposition in these 2 veins” Li et al (2025).
The story of propofol development – Full Text
“The introduction of propofol changed our understanding of pediatric anesthesia pharmacology, research approaches for intravenous drug study, and led to infusion pump development for the maintenance phase of anesthesia” Anderson and Cortinez (2025).
Postnatal umbilical cord blood sampling – Full Text
“Postnatal umbilical cord blood sampling (PCBS), rather than obtaining blood from the neonate, avoids significant neonatal blood loss at a critical time of extrauterine transition and prevents phlebotomy pain in infants without a catheter for blood drawing” Kaufman et al (2025).
Ultrasound-guided peripheral IV access performed by novice operators
“In a cohort of medical students with minimal prior experience in USGIV placement, biplane imaging was not associated with reduction in time to successful USGIV placement, but was associated with a reduction in posterior wall punctures” Thom et al (2025).
Student nurse experience of venepuncture and peripheral intravenous cannulation learning
“This study explores final-year nursing students’ experiences with venepuncture and peripheral intravenous cannulation, focusing on both educational and clinical practice settings” Hernon et al (2025).
Vascular Access and IV Therapy Resource

Taurolidine IV lock reduces recurrent CRBSI – Full Text
“This study demonstrates that the use of 1.35% taurolidine significantly reduces the rate of recurrent CRBSIs and CVC removals due to CRBSIs compared to 0.9% saline in adult patients with CIF reliant on HPS” Nerstrøm et al (2025).
Digitalised measures for CLABSI prevention compliance – Full Text
“Digitalised interventions for CLABSI prevention seem to be effective in reducing infection rates, likely because of increasing compliance to established guidelines for CLABSI prevention” Obama et al (2025).
Peripheral venous blood gas analysis Cochrane review – Full Text
“The primary objective of this review is to evaluate the performance of PVBGA by comparing it with the reference standard ABGA, which is assumed to be error-free for the diagnosis of (1) respiratory failure, (2) hypercarbia, and (3) metabolic disturbance (the three target conditions) in adults” Byrne et al (2025).
Blood culture contamination creep – Full Text
“In a low-COVID-19-burden secondary care teaching hospital setting, blood culture contamination rates have progressively increased over the past decade, irrespective of the pandemic. These findings underscore the importance of sustained vigilance in infection prevention and control practices, strict adherence to blood culture collection protocols, and the ongoing need for staff training” Jeverica et al (2025).
OPAT for patients with substance use disorder – Full Text
“Outpatient parenteral antimicrobial therapy (OPAT) is often withheld from individuals with substance use disorder (SUD), despite evidence suggesting similar outcomes. We investigated this using a large, nationwide claims database” Rogers et al (2025).
Prevention of central line infection among ICU nurses
“The educational intervention effectively improved ICU nurses’ knowledge regarding CLABSI prevention but did not significantly change their attitudes. Tailoring interventions to demographic characteristics may further enhance their effectiveness and contribute to better patient outcomes and healthcare quality” Alzoubi et al (2025).
Patient empowerment and CLABSI reduction
“To evaluate the impact of patient empowerment in reducing the incidence density (ID) of CLABSI” Reghini et al (2025).
Review of blood culture single-sampling strategy and initial specimen diversion – Full Text
“After combined implementation of SSS and initial specimen diversion (ISDT) in our region, we evaluated the proportion of sampling events with at least four bottles, with growth of relevant pathogens and with growth of coagulase-negative staphylococci (CoNS) before and after the intervention” Oldberg et al (2025).
Simulation for central venous catheterization training
“We hypothesized that resident physicians would prefer a simulation model with high functional task alignment over a model with higher superficial resemblance and lower functional task alignment in central venous catheter placement training” Gomaa et al (2025).
Management of a positive blood cultures
“There is considerable practice variation among ED physicians for the management of positive blood cultures in children across Canada. Incongruencies in the perceived impact of clinical factors on the likelihood of a true bacteremia, such as time-to-positivity, highlight the need for a standardized decision-making tool” Gouin et al (2025).
Technique for TIVAD implantation for chemotherapy
“This bicentric, retrospective study aims to compare the surgical vein cut-down approach with ultrasound-guided percutaneous vein puncture in terms of procedural success, complication rates, and operative efficiency” Fassari et al (2025).
The Irish national OPAT programme
“The study underscores the importance of national registries in monitoring and improving OPAT services and calls for integration of microbiological data to enhance stewardship” Reidy et al (2025).
Implantable port catheter detachment – Full Text
“The chest port was placed 10 months prior without complication. An initial fluoroscopic image of the chest revealed detachment and migration of the catheter towards the right atrium. The catheter was successfully retrieved with a gooseneck snare using an inferior approach through the femoral vein” Van Vorst et al (2025).
Central line placement in newborns
“Based on this initial experience, we conclude that ultrasound-guided innominate vein cannulation is feasible and safe for infants under 4.5 kg” D’ Alessandro et al (2025).
Venous blood collection guidelines
“The guideline includes practical tools, such as checklists and detailed information on sampling devices, to facilitate implementation. This initiative would help standardize blood collection practices, improve specimen quality, and enhance patient care by ensuring accurate laboratory results in clinical settings” Chang et al (2025).
Cardiac tamponade caused by misplaced PICC – Full Text
“To prevent fatal complications such as cardiac tamponade, PICCs should be positioned in safe area. Proper placement in the superior vena cava should be confirmed and maintained” Shin et al (2025).
Subcutaneous fluid administration in pediatric sepsis – Full Text
“In this case report, we describe a seven-week-old male infant with dehydration secondary to Escherichia coli pyelonephritis. After multiple failed IV attempts, even under general anesthesia, hypodermoclysis was performed” Taha et al (2025).
PICC tip malposition case study – Full Text
“We describe 2 unusual peripherally inserted central catheter (PICC) malpositions in the left thymic vein and the right middle thyroid vein, which are, to our knowledge, the first 2 cases of PICC malposition in these 2 veins” Li et al (2025).
The story of propofol development – Full Text
“The introduction of propofol changed our understanding of pediatric anesthesia pharmacology, research approaches for intravenous drug study, and led to infusion pump development for the maintenance phase of anesthesia” Anderson and Cortinez (2025).
Postnatal umbilical cord blood sampling – Full Text
“Postnatal umbilical cord blood sampling (PCBS), rather than obtaining blood from the neonate, avoids significant neonatal blood loss at a critical time of extrauterine transition and prevents phlebotomy pain in infants without a catheter for blood drawing” Kaufman et al (2025).
Ultrasound-guided peripheral IV access performed by novice operators
“In a cohort of medical students with minimal prior experience in USGIV placement, biplane imaging was not associated with reduction in time to successful USGIV placement, but was associated with a reduction in posterior wall punctures” Thom et al (2025).
Student nurse experience of venepuncture and peripheral intravenous cannulation learning
“This study explores final-year nursing students’ experiences with venepuncture and peripheral intravenous cannulation, focusing on both educational and clinical practice settings” Hernon et al (2025).
Improving venous access by using a near-infrared vein-finder – Full Text
“Based on our findings, we recommend providing an NIR vein-finder device and ultrasound training to improve venous access in hospital settings and encourage further research to evaluate their effectiveness” Bennakhi et al (2025).
Impact of sodium citrate lock therapy in patients receiving home parenteral nutrition
“We determined the incidence of catheter-related bloodstream infections in adult patients requiring home parenteral nutrition (HPN) while receiving sodium citrate locks” Leong et al (2025).
OPAT administration of intravenous ganciclovir
“Ganciclovir via OPAT is a viable option in patients requiring an extended duration of IV therapy. In our cohort of 18 patients, only one had early discontinuation of therapy due to ganciclovir-related AKI. Close monitoring of labs and an established OPAT protocol can allow for successful completion of therapy” Patel et al (2025).
Parenteral nutrition extravasation in newborns – Full Text
“We report two cases: one of neonatal hydrothorax with subsequent lung cystic formation after a parenteral nutrition leakage caused by the displacement of an Epicutaneo-Caval Catheter in the basilic vein of the left arm; the second involves a peritoneal collection of parenteral nutrition from the umbilical venous catheter” Coramusi et al (2025).
Impact of delayed blood culture transport time – Full Text
“There is a marginal loss of growth for every hour a blood culture is left unincubated, with the loss of recovery of Streptococcus pyogenes and other streptococci being most common. There was no evidence of a reduction in Gram-negatives, anaerobes, or yeasts” Deas et al (2025).
Survey of OPAT practices in France – Full Text
“This study aimed to assess the implementation and organization of Outpatient Parenteral Antimicrobial Therapy (OPAT) in France by examining the practices of community nurses (CNs)” Raux et al (2025).
Guidelines for intravenous iron therapy in heart failure patients – Full Text
“We aim to evaluate the implementation of the 2021 ESC Guidelines regarding screening and treatment of iron deficiency in patients with heart failure (HF) at Karolinska University Hospital” Gamage et al (2025).
Neonatal antibiotic therapy and patient safety – Full Text
“Specifically, studies that decrease the treatment length or advocate for the early transition of intravenous to oral antibiotics in all neonates with suspected or culture-positive sepsis or pneumonia should be regarded with caution” Lawrence et al (2025).