Use of Taurolidine in pediatric home parenteral nutrition patients

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In order to reduce the incidence of catheter-related bloodstream infections (CRBSI) in home parenteral nutrition patients, the use of taurolidine was introduced in the Sophia Children’s Hospital in 2011” Hulshof et al (2016).

Abstract:

In order to reduce the incidence of catheter-related bloodstream infections (CRBSI) in home parenteral nutrition patients, the use of taurolidine was introduced in the Sophia Children’s Hospital in 2011. This introduction led to a reduction in CRBSI: 12.7/1,000 catheter days before the use of taurolidine, compared with 4.3/1,000 catheter days afterwards (n=7) (relative risk=0.36, 95%CI: 0.20-0.65 (p= 0,018)).

Reference:

Hulshof, E.C., Hanff, L.M., Olieman, J., de Vette, S., Driessen, G.J., Meeussen, C. and Escher, J.C. (2016) Taurolidine In Pediatric Home Parenteral Nutrition Patients. The Pediatric Infectious Disease Journal. November 11th. [Epub ahead of print].

DOI: 10.1097/INF.0000000000001404

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