Upper extremity deep venous thrombosis after implantable port insertion

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Although their use has been associated with upper extremity deep venous thrombosis, the risk factors of upper extremity deep venous thrombosis in patients with a port are not studied adequately” Tabatabaie et al (2017).

Abstract:

BACKGROUND: Totally implantable venous access devices (ports) are widely used, especially for cancer chemotherapy. Although their use has been associated with upper extremity deep venous thrombosis, the risk factors of upper extremity deep venous thrombosis in patients with a port are not studied adequately.

METHODS: The Healthcare Cost and Utilization Project’s Florida State Ambulatory Surgery and Services Database was queried between 2007 and 2011 for patients who underwent outpatient port insertion, identified by Current Procedural Terminology code. Patients were followed in the State Ambulatory Surgery and Services Database, State Inpatient Database, and State Emergency Department Database for upper extremity deep venous thrombosis occurrence. The cohort was divided into a test cohort and a validation cohort based on the year of port placement. A multivariable logistic regression model was developed to identify risk factors for upper extremity deep venous thrombosis in patients with a port. The model then was tested on the validation cohort.

RESULTS: Of the 51,049 patients in the derivation cohort, 926 (1.81%) developed an upper extremity deep venous thrombosis. On multivariate analysis, independently significant predictors of upper extremity deep venous thrombosis included age

CONCLUSION: This study identified major risk factors of upper extremity deep venous thrombosis. Further studies are needed to evaluate the appropriateness of thromboprophylaxis in patients at greater risk of upper extremity deep venous thrombosis.

Reference:

Tabatabaie, O., Kasumova, G.G., Kent, T.S., Eskander, M.F., Fadayomi, A.B., Ng, S.C., Critchlow, J.F., Tawa, N.E. and Tseng, J.F. (2017) Upper extremity deep venous thrombosis after port insertion: What are the risk factors? Surgery. May 20th. [Epub ahead of print].

doi: 10.1016/j.surg.2017.02.020.

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