Sixty-one percent of intravenous drug users fail OPAT treatment

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Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment” Buehrle et al (2017).

Abstract:

Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated with failure (P = .04). Intravenous drug users requiring OPAT are at high risk for failure; additional studies are needed to explore alternatives.

Reference:

Buehrle, D.J., Shields, R.K., Shah, N., Shoff, C. and Sheridan, K. (2017) Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users. Open Forum Infectious Diseases. 4(3), p.ofx102. eCollection 2017 Summer.

doi: 10.1093/ofid/ofx102.

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