Prophylactic anticoagulation and PICC-related upper extremity venous thrombosis

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“The evidence regarding the value of prophylactic anticoagulation to prevent peripherally inserted central catheter-related upper extremity venous thrombosis (PRUEVT) is inconsistent.” Wilson and Alred (2014).

Reference:

Wilson, J.D. and Alred, S.C. (2014) Does Prophylactic Anticoagulation Prevent PICC-Related Upper Extremity Venous Thrombosis? A Case-Control Study. Journal of Infusion Nursing. 37(5), p.381-385.

Abstract:

The evidence regarding the value of prophylactic anticoagulation to prevent peripherally inserted central catheter-related upper extremity venous thrombosis (PRUEVT) is inconsistent. The authors reviewed 3 years of data, identifying all cases of PRUEVT at a facility in Texas, and individually matched each for risk factors with 2 controls. Not being on any form of anticoagulant or antiplatelet agent was associated with a modestly increased risk of PRUEVT (odds ratio 1.93, P = .036, 95% confidence interval, 1.025-3.602). Each approach to thrombosis prevention showed a trend toward a protective effect, but none reached statistical significance individually.

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