Preventing CLABSI in home parenteral nutrition patients

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“Home parenteral nutrition (HPN) patients are at particularly high risk of meticillin-sensitive Staphylococcus aureus (MSSA) catheter-related bloodstream infections (CRBSI). We developed a multi-disciplinary enhanced care pathway encompassing a number of minimal cost interventions involving line/exit site care, training for staff and parents, multi-disciplinary discharge planning and monitoring compliance.” Muir et al (2014).

Reference:

Muir, A., Holden, C., Sexton, E. and Gray, J.W. (2014) Preventing Bloodstream Infection in Home Parenteral Nutrition Patients. Journal of Pediatric Gastroenterology and Nutrition. 2014 May 1. [epub ahead of print].

Abstract:

Home parenteral nutrition (HPN) patients are at particularly high risk of meticillin-sensitive Staphylococcus aureus (MSSA) catheter-related bloodstream infections (CRBSI). We developed a multi-disciplinary enhanced care pathway encompassing a number of minimal cost interventions involving line/exit site care, training for staff and parents, multi-disciplinary discharge planning and monitoring compliance. Implementation reduced the mean rates of MSSA CRBSI (from 0.93, 95% CI 0.25-1.61, to 0.23/1000 PN days, 95% CI -0.06-0.52) and all-cause CRBSI (from 1.98, 95% CI 0.77-3.19, to 0.45/1000 PN days, 95% CI 0.10-0.80). A similar approach could be applied to preventing healthcare-associated infections in other complex, vulnerable patient groups.

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