This study demonstrates superior nutrient intake and growth in the first two weeks of life for infants who received nutrition via PICC line” Smazal et al (2016).
BACKGROUND: While very preterm (<32 weeks gestation) infants are routinely provided intensive nutritional support via central line, clinical practice varies for nutrient delivery in infants born moderately preterm (32 to 34 weeks gestation). We sought to define the impact of nutritional support via peripherally inserted central catheter (PICC) on nutrient delivery in the first two weeks of life and growth by discharge.
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METHODS: Data were extracted from the records of 187 infants born between 32 and 34 6/7 weeks gestation and admitted to the University of Iowa Children’s Hospital between April 2012 and December 2013. Records of all feedings, weights, and PICC placements were collected. The growth outcomes at discharge for infants who received nutrition via PICC were compared to those who did not.
RESULTS: In the first week of life, newborns who received nutrition via PICC line received 17.6 more kilocalories (CI 12.5-22.7, p<0.001) and 1.2 more grams protein per kilogram body weight per day (CI 0.9-1.4, p<0.001) compared to control infants. By discharge, the PICC group had gained 302 grams more body weight (p<0.001).
CONCLUSIONS: This study demonstrates superior nutrient intake and growth in the first two weeks of life for infants who received nutrition via PICC line.
Smazal, A.L., Kavars, A.B., Carlson, S.J., Colaizy, T.T. and Dagle, J.M. (2016) Peripherally inserted central catheters optimize nutrient intake in moderately preterm infants. Pediatric Research. April 8th. [Epub ahead of print].
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