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PICC line complication rates among preterm infants

To examine whether there is an association between peripherally inserted central venous catheter (PICC) insertion site and complication rates among preterm infants” Bashir et al (2016).

Abstract:

Objective: To examine whether there is an association between peripherally inserted central venous catheter (PICC) insertion site and complication rates among preterm infants.

Design: We performed a retrospective analysis of the first PICCs placed in preterm infants in a tertiary neonatal intensive care unit between January 2006 and December 2010. The PICC-related complications resulting in catheter removal were compared based on site of insertion.

Results: Of the 827 PICCs, 593 (72%) were inserted in upper extremity. Lower extremity PICC group infants had higher illness severity (SNAP-II) score and more likely to be inserted later as compared with the upper extremity group. There was no significant difference in the total PICC-related complications between upper and lower extremity PICCs (31.3 vs. 26%; p > 0.05). Logistic regression analysis after adjusting for gestational age, day of line insertion, and SNAP-II score revealed that upper extremity PICCs were associated with increased risk of line infiltration (adjusted odds ratio , 2.41; 95% confidence interval , 1.36-4.29) but not the total PICC complication (aOR, 1.29; 95% CI, 0.91-1.83).

Conclusion: There is no difference in total PICC-related complication between upper and lower extremity PICCs; however, the PICC-related mechanical complications vary depending on the site of insertion in preterm infants.

Reference:

Bashir, R.A., Swarnam, K., Vayalthrikkovil, S., Yee, W. and Soraisham, A.S. (2016) Association between Peripherally Inserted Central Venous Catheter Insertion Site and Complication Rates in Preterm Infants. American Journal of Perinatology. April 8th. .

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