Patients with multiple central venous catheters are at 6.2 times higher risk of thrombosis

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“Patients with multiple CVLs are at 6.2 times higher risk of developing thrombosis compared with those with a single CVL.” Altassan et al (2014).

Reference:

Altassan, R., Al Alem, H. and Al Harbi, T. (2014) Temporary central line related thrombosis in a pediatric intensive care unit in central Saudi Arabia. Two-year incidence and risk factors. Saudi Medical Journal. 35(4), p.371-6.

Abstract:

OBJECTIVE: To estimate the incidence of temporary central venous line (CVL) related thrombosis among the pediatric population of critical care units, and to determine the possible predictors for developing CVL thrombosis.

METHODS: A retrospective cohort study of patients

RESULTS: In 2 years, there were 1,361 admissions to the PICU. Only 248 patients required a central line for acute management. Twenty-one (8.5%) patients developed a thrombosis. The risk of thrombosis increased with multiple insertions of the central line compared with a single central line insertion (95% confidence interval: 2.339-16.667; p=0.0003).

CONCLUSION: Among all predictors, the number of CVLs was the only significant predictor of CVL thrombosis. Patients with multiple CVLs are at 6.2 times higher risk of developing thrombosis compared with those with a single CVL.

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