Neonatal candida krusei fungemia tracked to an infusate

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“We report an outbreak of C krusei fungemia in the neonatal Intensive care unit (ICU) of our hospital over a short period of 2 weeks” Rongpharpi et al (2014).

Reference:

Rongpharpi, S.R., Gur, R., Duggal, S., Kumar, A., Nayar, R., Xess, I., Wadhwa, V. and Khanijo, C.M. (2014) Candida krusei fungemia in 7 neonates: Clonality tracked to an infusate. American Journal of Infection Control. 42(11), p.1247–1248.

Abstract:

Fungemia is considered a major cause of neonatal morbidity and mortality. Candida krusei is an infrequent isolate among healthy hosts, but is a pathogen of concern among immunocompromised patients, in whom it can cause fungemia, endopthalmitis, arthritis, and endocarditis.1 It is difficult to treat owing to intrinsic fluconazole resistance and variable susceptibility to flucytosine and amphotericin B.2 We report an outbreak of C krusei fungemia in the neonatal Intensive care unit (ICU) of our hospital over a short period of 2 weeks.

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