Management of intrapleural extravasation of cytotoxic chemotherapy

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Unfortunately, if such extravasation occurs into the pleural space, limited data is available to guide appropriate management” Aguirre et al (2017).

Abstract:

The extravasation of cytotoxic agents into subcutaneous tissue is a serious complication of chemotherapy. Unfortunately, if such extravasation occurs into the pleural space, limited data is available to guide appropriate management. We present the first report in the literature of video-assisted thoracoscopy combined with a topoisomerase II inhibitor and iron chelator, dexrazoxane, in the successful management of this complication.

Reference:

Aguirre, V.J., Barnett, D., Burdett, N., Joshi, R. and Viana, F.F. (2017) Video-assisted thoracoscopy in the management of intrapleural extravasation of cytotoxic chemotherapy. Thoracic Cancer. March 31st. [Epub ahead of print].

doi: 10.1111/1759-7714.12430.

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