“This study investigated whether Certofix(®) protect antimicrobial catheters carry a surface charge and whether this inhibits biofilm formation.” Richards et al (2014).
Richards, G.A., Brink, A.J., McIntosh, R., Steel, H.C. and Cockeran, R. (2014) Investigation of biofilm formation on a charged intravenous catheter relative to that on a similar but uncharged catheter. Medical Devices (Auckland, N.Z.). 7, p.219-24. eCollection 2014.
Investigation of biofilm formation on a surface charged intravenous catheter http://ctt.ec/2bn4L+ @ivteam #ivteam
Catheter-related blood stream infections increase morbidity, mortality, and costs. This study investigated whether Certofix(®) protect antimicrobial catheters carry a surface charge and whether this inhibits biofilm formation. The capacitance of the catheter surfaces was measured and, to determine if the catheters released ions, distilled water was passed through and current measured as a function of voltage. With probes touching the inner and outer surfaces, capacitance was not voltage-dependent, indicating surfaces were uncharged or carried a similar charge. When one probe penetrated the catheter wall, capacitance was weakly voltage-dependent, indicating the presence of a surface charge. Standard and charged catheters were also exposed to phosphate buffered saline as controls or 2×10(6) colony forming units/mL (in phosphate buffered saline) of six different microorganisms for 60 or 120 minutes. When the growth of detached bacteria was measured, biofilm formation was significantly reduced, (P<0.05), for charged catheters for all organisms.
Other intravenous and vascular access resources that may be of interest (External links – IVTEAM has no responsibility for content).
- Guide for intravenous chemotherapy and associated vascular access devices from Macmillan.
- CancerUK IV chemotherapy information.