How to manage central line associated venous thrombosis in children

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Central venous catheters (CVCs) account for the largest proportion of thrombotic events in pediatric patients. Questions remain regarding adequate treatment and prevention methods” Witmer et al (2016).

Abstract:

Central venous catheters (CVCs) account for the largest proportion of thrombotic events in pediatric patients. Questions remain regarding adequate treatment and prevention methods. We surveyed pediatric hematology/oncology specialists, using hypothetical cases to assess management strategies for acute CVC thrombosis and secondary prevention.

Survey respondents varied in the use of the thrombophilia evaluation (33.3%, 41/123) and duration of treatment (6 weeks: 54.1%, 66/122). Secondary CVC prophylaxis was utilized by 36.6% (45/123) of respondents and by 24.4% (30/123) but only if there was a documented thrombophilia. This heterogeneity highlights the need for clinical studies to address these important clinical questions.

Reference:

Witmer, C.M., Sauck, E. and Raffini, L.J. (2016) A survey of pediatric hematology/oncology specialists regarding management of central line associated venous thrombosis. Paediatric Blood & Cancer. December 1st. [epub ahead of print].

DOI: 10.1002/pbc.26383

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