Does a dedicated lumen for parenteral nutrition reduce CRBSI risk?

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Publications reviewed by the authors reported comparative rates of catheter-related bloodstream infection (CR-BSI) in patients with CVADs who received PN through a dedicated lumen compared with those who had PN administered through multilumen CVADs” Gavin et al (2018).

Abstract:

Guidelines recommend using single-lumen central vascular access devices (CVADs) for the administration of parenteral nutrition (PN) or lipid-based solutions, or a dedicated lumen on a multilumen CVAD. Publications reviewed by the authors reported comparative rates of catheter-related bloodstream infection (CR-BSI) in patients with CVADs who received PN through a dedicated lumen compared with those who had PN administered through multilumen CVADs. Two studies included 650 patients with 1349 CVADs. CR-BSIs were equally distributed between the 2 groups. Both studies were poorly reported and had significant risk of bias. These results should be interpreted with caution.



Reference:

Gavin, N.C., Button, E., Castillo, M.I., Ray-Barruel, G., Keogh, S., McMillan, D.J. and Rickard, C. (2018) Does a Dedicated Lumen for Parenteral Nutrition Administration Reduce the Risk of Catheter-Related Bloodstream Infections? A Systematic Literature Review. Journal of Infusion Nursing. 41(2), p.122–130.

doi: 10.1097/NAN.0000000000000270

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