Complications of peripherally inserted central catheters in adults with respiratory conditions

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“Peripherally inserted central catheters (PICCs) are increasingly used in patients with cystic fibrosis (CF) or with non-CF bronchiectasis, but little data exist on catheter-related complications in this setting” Dupont et al (2015).

Reference:

Dupont, C., Gouya, H., Panzo, R., Hubert, D., Correas, J.M., Agrario, L., Chapron, J., Honoré, I., Kanaan, R., Legmann, P., Dusser, D., Vignaux, O. and Burgel, P.R. (2015) Complications of peripherally inserted central catheters in adults with cystic fibrosis or bronchiectasis. The Journal of Vascular Access. February 4th. [epub ahead of print].

Abstract:

BACKGROUND: Peripherally inserted central catheters (PICCs) are increasingly used in patients with cystic fibrosis (CF) or with non-CF bronchiectasis, but little data exist on catheter-related complications in this setting.

METHODS: Prospective follow-up of consecutive PICCs inserted for intravenous (IV) antibiotics in adults with CF or with non-CF bronchiectasis at Cochin Hospital (Paris, France).

RESULTS: Between March 2009 and December 2011, 182 PICCs were prescribed in 117 adults (67 CF and 50 non-CF patients). Ultrasound-guided placement of catheter was successful in 174/182 (95.6%) procedures; no insertion complication occurred. The mean ± SD catheter dwell time was 15 ± 9 days. No catheter-associated bloodstream infection occurred; main complications were symptomatic upper limb deep vein thrombosis (2%), catheter obstruction (18%) and persistent pain after catheter insertion (18%). Patients’ satisfaction was high and PICC could be used to perform antibiotic courses in most patients.

CONCLUSIONS: PICCs were generally safe for performing IV antibiotic courses in patients with CF or non-CF bronchiectasis, but prolonged pain and/or catheter obstruction occurred in approximately 20% of cases.

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