CLABSI risk and needleless intravenous connectors meta-analysis

0

First published on IVTEAM 29th November 2014.

Repeat publication as full text available.

Full Text

Reference:

Tabak, Y.P., Jarvis, W.R., Sun, X., Crosby, C.T. and Johannes, R.S. (2014) Meta-analysis on central line–associated bloodstream infections associated with a needleless intravenous connector with a new engineering design. American Journal of Infection Control. 42(12), p.1278–1284.

Abstract:

Highlights: Improved engineering design of needleless intravenous connectors that facilitate effective intravenous line care, disinfection, and management are associated with a lower risk of central line–associated bloodstream infections.

Background: Intravenous needleless connectors (NCs) with a desired patient safety design may facilitate effective intravenous line care and reduce the risk for central line–associated bloodstream infection (CLA-BSI). We conducted a meta-analysis to determine the risk for CLA-BSI associated with the use of a new NC with an improved engineering design.

Methods: We reviewed MEDLINE, Cochrane Database of Systematic Reviews, Embase, ClinicalTrials.gov, and studies presented in 2010-2012 at infection control and infectious diseases meetings. Studies reporting the CLA-BSIs in patients using the positive-displacement NC (study NC) compared with negative- or neutral-displacement NCs were analyzed. We estimated the relative risk of CLA-BSIs with the study NC for the pooled effect using the random effects method.

Results: Seven studies met the inclusion criteria: 4 were conducted in intensive care units, 1 in a home health setting, and 2 in long-term acute care settings. In the comparator period, total central venous line (CL) days were 111,255; the CLA-BSI rate was 1.5 events per 1,000 CL days. In the study NC period, total CL days were 95,383; the CLA-BSI rate was 0.5 events per 1,000 CL days. The pooled CLA-BSI relative risk associated with the study NC was 0.37 (95% confidence interval, 0.16-0.90).

Conclusion: The NC with an improved engineering design is associated with lower CLA-BSI risk.

Thank you to our partners for supporting IVTEAM

Share.

Comments are closed.

Free Email Updates
Join 5.5K IVTEAM members. Subscribe now and be the first to receive all the latest free updates from IVTEAM!
100% Privacy. We don't spam.