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"We retrospectively compared risk factors for unplanned removal of two commonly used CVCs, peripherally inserted central catheters (PICCs) and tunneled CVCs, to propose which is the better device" Miyagishima et al (2022).

Catheter occlusion rates by CVC type

Abstract:

Central venous catheters (CVCs) are essential devices in the treatment of pediatric patients with hematological and oncological disorders; however, the most suitable type of CVC for these patients remains unclear. We retrospectively compared risk factors for unplanned removal of two commonly used CVCs, peripherally inserted central catheters (PICCs) and tunneled CVCs, to propose which is the better device. We followed 89 patients fitted with a tunneled CVC (total 21,395 catheter-days) and 84 fitted with a PICC (total 9177 catheter-days) between January 1, 2013 and December 31, 2015, until catheter removal. Patients with a PICC had a significantly higher 3-month cumulative incidence of catheter occlusion (5.2% vs. 0%, p = 4.08 × 10-3) and total unplanned removals (29.0% vs. 6.9%, p = 0.0316) than those with tunneled CVCs. However, the cumulative incidence of central line-associated bloodstream infection did not differ significantly by CVC type. Multivariable analysis identified younger age (< 2 years) and PICC (SHR 2.73; 95% CI 1.48-5.02) as independent risk factors for unplanned removal. Thus, our results suggest that tunneled CVCs are preferable in pediatric patients with hematological and oncological disorders requiring long-term, intensive treatment.


Reference:

Miyagishima M, Hamada M, Hirayama Y, Muramatsu H, Tainaka T, Shirota C, Hinoki A, Imaizumi T, Nakatochi M, Kamei M, Nishikawa E, Kawashima N, Narita A, Nishio N, Kojima S, Takahashi Y. Risk factors for unplanned removal of central venous catheters in hospitalized children with hematological and oncological disorders. Int J Hematol. 2022 Jun 21. doi: 10.1007/s12185-022-03346-4. Epub ahead of print. PMID: 35727532.