The following morning, light brown skin staining was noted at the infusion site, and the staining was present 2 months later at follow-up. Skin staining following intravenous iron infusion is a rare but important side effect” Crowley et al (2019).
Abstract:
This report describes the case of a 36-year-old woman, gravida 3, para 2, at 11 weeks’ gestation, who received a ferric carboxymaltose infusion for iron deficiency anaemia after medical management of a miscarriage. The following morning, light brown skin staining was noted at the infusion site, and the staining was present 2 months later at follow-up. Skin staining following intravenous iron infusion is a rare but important side effect. The skin staining is potentially permanent but may fade in time. Such an adverse effect may have cosmetic consequences for the patient.
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Reference:
Crowley, C.M., McMahon, G., Desmond, J. and Imcha, M. (2019) Skin staining following intravenous iron infusion. BMJ Case Reports. 12(6), p.e229113. doi: 10.1136/bcr-2018-229113.