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"Occlusion is an important complication because it occurred in more than half of the catheters and was one of the main reasons for withdrawal" Souza and Silva (2021).
Abstract:

Objective: To analyze the occurrence of occlusions in peripherally inserted central venous catheters in pediatric patients in antineoplastic chemotherapy.

Method: Retrospective cohort, with 156 medical records of patients aged 0-19 years who underwent outpatient chemotherapy between 2013 and 2017 by this catheter, in a hospital in the city of Rio de Janeiro. Descriptive and inferential statistics were applied.

Results: 219 catheters were registered. Occlusion occurred in 141 (64.4%) catheters; 63 (44.7%) were removed because of occlusion, either alone or associated with another factor. Total occlusion alone led to the removal of 27 (12.3%) catheters. Occlusion was associated with: catheter dwell time, cyclophosphamide, neuroblastoma, bone metastasis and number of chemotherapy sessions.

Conclusion: Occlusion is an important complication because it occurred in more than half of the catheters and was one of the main reasons for withdrawal. The identified risk factors may guide the care to prevent this complication.

Reference:

Souza BICC, Silva MMD. Occlusions in peripherally inserted central venous catheters in pediatric patients in antineoplastic chemotherapy. Rev Gaucha Enferm. 2021 Mar 29;42:e20190495. English, Portuguese. doi: 10.1590/1983-1447.2021.20190495. PMID: 33787760.