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"The tip of the PICC appeared displaced into the internal jugular vein in the early phase and was placed on the superior vena cava in the delayed phase" Akatsuka et al (2021).
PICC displacement after contrast injection

Extract:

“A peripherally inserted central catheter (PICC) was inserted through the right basilic vein and placed within the superior vena cava of a patient for fluid and medication administration during postoperative management of bladder cancer.

Following the development of sepsis, contrast-enhanced CT was performed to detect infectious foci. The tip of the PICC appeared displaced into the internal jugular vein in the early phase and was placed on the superior vena cava in the delayed phase (figure 1). In the second CT scan performed 2 days later, the tip of the PICC had moved again in the early phase, resulting in it being placed on the superior vena cava in the delayed phase (figure 2). The rates of contrast injection for the first and second CT scans were 4.1 mL/s and 4.7 mL/s, respectively.”

Reference:

Akatsuka M, Tatsumi H, Yama N, Masuda Y. Displacement of a peripherally inserted central catheter after injection of contrast media. BMJ Case Rep. 2021 Sep 29;14(9):e246068. doi: 10.1136/bcr-2021-246068. PMID: 34588207.