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"To reduce PICC-related BSIs and their related mortality, it is important to limit the overuse of PICCs and to implement a 'no PICC' policy by limiting the insertion of PICCs to situations without other available options" Durand et al (2020).

Abstract:

In our institution, between January 2010 and December 2017, 15 140 peripherally inserted central catheters (PICCs) were inserted in 12 314 patients. Using time-series analysis to evaluate the annual historical trend (AHT), we observed a significant increase in bloodstream infections (BSIs; AHT = 24; p < 0.001) and associated deaths (AHT = 3; p 0.02) in patient with PICCs. The risk of experiencing a BSI was significantly higher in patients with PICCs (odds ratio = 9.6; 95% confidence interval, 9.08-10.18; p < 0.001). To reduce PICC-related BSIs and their related mortality, it is important to limit the overuse of PICCs and to implement a 'no PICC' policy by limiting the insertion of PICCs to situations without other available options.

Reference:

Durand, G.A., Abat, C., Cassir, N., Jimeno, M.T., Vidal, V., Fenollar, F., Brouqui, P. and Raoult, D. (2020) Peripherally inserted central catheters: a hidden emerging cause of infection outbreaks. New Microbes and New Infections. 35, p.100671. doi: 10.1016/j.nmni.2020.100671. eCollection.