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"OPAT antibiotics with less cumbersome administration regimens may translate into higher patient satisfaction and quicker return to life normalcy" Wu et al (2021).
OPAT vancomycin and daptomycin comparison

Abstract:

A 5-question telephone survey was administered to compare satisfaction between patients receiving vancomycin vs daptomycin outpatient parenteral antimicrobial therapy (OPAT). Twenty-seven patients completed the survey (40%). Vancomycin had higher daily interference score than daptomycin (P = .03). All patients receiving daptomycin reported a satisfaction score ≥8/10, as compared to 67% of patients who received vancomycin (P < .03). OPAT antibiotics with less cumbersome administration regimens may translate into higher patient satisfaction and quicker return to life normalcy.

Reference:

Wu KH, Sakoulas G, Geriak M. Vancomycin or Daptomycin for Outpatient Parenteral Antibiotic Therapy: Does It Make a Difference in Patient Satisfaction? Open Forum Infect Dis. 2021 Aug 30;8(8):ofab418. doi: 10.1093/ofid/ofab418. PMID: 34476284; PMCID: PMC8404740.