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CVCs may be associated with insertion-related, mechanical, thrombotic, and infection-related complications that, in turn, are associated with higher mobidiity and mortality, and increased healthcare costs” Levy et al (2019).

Extract:

Central venous catheters (CVCs), including nontunneled CVCs, peripherally inserted central catheters (PICCs), and tunneled or implanted central access devices, are commonly used in pediatrics for emergent, short-term, and long-term indications. CVCs may be associated with insertion-related, mechanical, thrombotic, and infection-related complications that, in turn, are associated with higher mobidiity and mortality, and increased healthcare costs [1–6]. These complications may be competing risks because the choice of CVC insertion site affects the risk of thrombotic and infection-related complications differently [7]. These complications are also additive. For…

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Reference:

Levy, E.R., Hutchins, K.A., Schears, G.J., Rodriguez, V. and Huskins, W.C. (2019) How We Approach Central Venous Catheter Safety: A Multidisciplinary Perspective. Journal of the Pediatric Infectious Diseases Society. December 30th. doi: 10.1093/jpids/piz096. [Epub ahead of print].