Subcutaneous rehydration in children

January 21, 2010

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Intravenous literature: Medscape.com highlight “Basco W.T. Subcutaneous Rehydration in Children — Feasible and Safe?

Study Summary:

Oral rehydration is the preferred method for dehydrated children, but many still require parenteral rehydration. Although subcutaneous delivery of fluids has been evaluated in adult patients, there are relatively less data on the safety and acceptability of this method in children. A clear advantage of subcutaneous delivery is that access is much easier to obtain than intravenous access, and the training needed to ensure successful insertion is minimal. The drug tested here was recombinant hyaluronidase, designed to decrease subcutaneous tissue resistance to fluid. The drug is given at the infusion site before delivery of fluids. This study sought to evaluate the efficacy, safety, and usefulness of the recombinant hyaluronidase in a population of children with mild or moderate dehydration… Click here for more.