Reducing the risk of implantable port catheter fracture
For subcutaneously implanted central venous ports, some complications due to prolonged placement have been reported. We investigated the appropriate puncture points and port placement sites
Pharmacokinetics of Cefazolin and Vancomycin in Infants
There is little evidence to describe the optimal dosing regimen for surgical site infection prophylaxis in infants undergoing cardiac surgery, and a great deal of
Use of epinephrine during neonatal resuscitation
Strong evidence from large clinical trials is lacking owing to the infrequent use of epinephrine during neonatal resuscitation” Vali et al (2019). Abstract: Epinephrine is
Clinical procedure course for medical students
This clinical procedures course introduces students to several basic diagnostic and therapeutic procedures, both invasive and noninvasive. These include managing pediatric and adult airways, starting
Clinical evaluation of two central venous catheter stabilization systems
We report a comparison of a suture-free system with standard sutures for securing short-term CVC in an international multicentre, prospective, randomized, non-blinded, observational feasibility study”
Mathematical model determines efficacy of three drug infusion methods
A mathematical model for the treatment of cancer using chemovirotherapy is developed with the aim of determining the efficacy of three drug infusion methods: constant,
Cost-effectiveness-analysis of ultrasound guidance for central venous catheterization
Because from the German perspective, the cost-effectiveness of ultrasound guidance is unclear, this study examined the cost-effectiveness of ultrasound guidance versus the landmark method for
Pharmacokinetics and pharmacodynamics of piperacillin in critically ill patients
This study aimed to characterize the population pharmacokinetics (PKs) of piperacillin and investigate probability of target attainment (PTA) and cumulative fraction of response (CFR) of
Ethanol as an additive in chemotherapy formulations
Some chemotherapy formulations contain ethanol as a solvent which can become relevant for medical and nonmedical reasons. Only a few studies have tried to quantify
Outcomes associated with peripheral IV bacteremia
We describe incidence rates, risk factors, and outcomes related to PVC-associated Staphylococcus aureus bacteremia (SAB), a common cause of hospital-onset (HO) SAB” Blauw et al
Chlorhexidine disinfectant reduces risk of central venous catheter infection
Assess the efficacy of chlorhexidine with povidone solutions as a skin disinfectant for central venous catheter (CVC) care” Shi et al (2019). Abstract: OBJECTIVE: Assess
Dalbavancin may be an alternative option for deep sternal wound infection
Dalbavancin may be an alternative option for DSWI caused by gram-positive bacteria when first line treatments are contraindicated or as a salvage treatment” Bartoletti et
Antidepressant effects of a single ketamine infusion evaluated
Repeated ketamine infusions have cumulative and sustained antidepressant effects. Reductions in depressive symptoms were maintained among responders through once-weekly infusions” Phillips et al (2019). Abstract:
Review looks at the safety of oral and intravenous iron
Intravenous iron is being used more frequently to replete iron stores. True anaphylaxis is very rare, but complement-mediated infusion reactions may be seen in up
Comparative efficacy of antimicrobial dressings and securement devices
The purpose of our study is to carry out a Bayesian network meta-analysis comparing the efficacy of different antimicrobial dressings for prevention of catheter-related blood
Impact of chlorhexidine gluconate on the skin microbiota of children and adults
We observed no differences in pediatric patients; however, multiple genera of bacteria were observed to be significantly less abundant in the adults bathing with CHG”
Effect of two tourniquet techniques on peripheral IV cannulation
Elastic tourniquets (ETs) and blood pressure cuffs (BPCs) are frequently used for venodilation. Although BPCs lead to increased venodilation and decreased compressibility, it is unclear
Detection of antibiotic resistance genes from blood cultures
We assessed ELITe MGB® assays in blood culture workflow to detect main carbapenemase and ESBL genes, Staphylococcus aureus and mec genes in less than 3h”
Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol
In critically ill patients, 2% chlorhexidine-alcohol is superior to 5% povidone iodine-alcohol for skin preparation before central venous and arterial catheters; whether this finding can
Vascular access decision algorithm is not superior to clinician judgment
The results of this study indicate that the quality improvement intervention and algorithm decision-making tool did not improve accuracy of use of access devices” Panter
Percutaneous removal of a precariously placed pericardial PICC
This case describes an unusual complication of peripherally inserted central catheter perforation into the pericardial space with subsequent successful percutaneous removal” Tyner et al (2019).
Anti-suicidal efficacy of repeated ketamine infusions
We confirmed that six repeated ketamine infusions for Chinese suicidal depressed patients were effective in generating a rapid response of suicidal ideation, especially low SI
How to prevent phlebotomy blood sample rejection?
There is an increasing amount of blood sample rejection at primary health care facilities (PHCFs), impacting negatively the staff, facility, patient and laboratory costs” Abbas
What is the effect of medical clowns on distress levels associated with venipuncture in children?
In this pilot study, medical clowns reduced the distress from venipuncture in children. No effect on cortisol levels was observed” Rimon et al (2016). Abstract:
Will repeated venipuncture increase risk for anaemia?
Anemia is a potential adverse effect of phlebotomy during participation in research. Clinical studies of acute HIV infection (AHI) require frequent phlebotomy to maximize scientific
Continuous closed circle television to monitor hand hygiene compliance
In the present study, we compare continuous closed circle television (CCTV) with overt observation for monitoring the hand hygiene compliance of health care workers (HCWs)
Resuscitation technical skill evaluation tool includes intraosseous needle insertion
To develop a reliable and validated tool to evaluate technical resuscitation skills in a pediatric simulation setting” Faudeux et al (2017). Abstract: OBJECTIVES: To develop
Effectiveness of PICC for intravenous calcium supplements after parathyroidectomy
PICC is a safe and efficient alternative in contrast to CVC for providing venous access for calcium supplementation in surgical patients after parathyroidectomy” Qi et
Effectiveness of HAI bundles reviewed in this article
The use of standardized care bundles is evidence-based; however, implementation of these bundles has not proven effective in eliminating HAIs” Bogue and Bogue (2017). Abstract:
How effective is OPAT treatment of osteomyelitis with telavancin
These data demonstrate the effective and safe OPAT use of telavancin, providing an alternative for successful treatment of patients with osteomyelitis” Schroeder et al (2017).
Using chlorhexidine skin disinfectant in extremely preterm infants
Using 0.2% CHG-acetate as skin disinfectant in extremely preterm infants resulted in statistically significant reduction of skin lesions, without increasing the risk of CLABSI as
PICC-related-thrombosis during induction chemotherapy in acute lymphocytic leukemia children
To investigate the current status of catheter-related-thrombosis (CRT) and the risk factors of Chinese acute lymphocytic leukemia (ALL) children with peripherally inserted central catheter (PICC)”
Complication rates of 3% hypertonic saline infusion through peripheral IV access devices
Although central venous infusion may reduce the risk of these minor complications, it may increase the risk of more serious complications such as large vessel
Reducing central venous catheter use in apheresis
This quality improvement project demonstrated that a successful apheresis procedure can be achieved easily and safely in the majority of PBSC donors preventing the potential
Ultrasound guidance for central venous access in children
This article aims to review the literature and evaluate the benefit of US guidance in the placement of CVCs, specifically in pediatric emergency department patients,
Impact of Taurolidine/Citrate locks for primary prevention of catheter-related infections
The ATAPAC study was a prospective, randomized, monocentric, phase IV trial evaluating the efficacy of taurolidine lock solution versus standard saline solution for primary TIVAP-RI
Mechanical complications of central venous catheterisation in a developing world setting
The aim of our study was to determine the spectrum of mechanical complications in a high-volume trauma centre in a developing world setting where ultrasound
What is the incidence of chlorhexidine resistance genes
Dressings containing chlorhexidine gluconate (CHG) are increasingly used in clinical environments for prevention of infection at central venous catheter insertion sites. Increased tolerance to this
Seroconversion rates among health care workers exposed to hepatitis C virus
This study provides the largest and most recent cohort from a major U.S. academic medical center. The seroconversion rates among HCP exposed to HCV-contaminated body
What are the differences between open and closed intravenous cannulae
This article explains the differences between open cannulae and closed cannulae. It reviews the current use of open cannulae and the risks of blood exposure
Case study describes radial nerve injury after venipuncture
We report the case of a 51-year-old female who experienced a sharp, painful, burning sensation down her arm at the time of needle insertion into
Risk assessment of pediatric venous thromboembolism
Although the overall incidence of VTE is estimated at 0.07-0.49 per 10,000 children, higher rates are observed in specific populations including hospitalized children, those with
Synthetic antimicrobial peptide central catheter lock solution
Here, we demonstrate that antimicrobial peptides (AMPs) are an effective antibiofilm treatment when applied as catheter lock solutions (CLSs) against S. aureus biofilm infections” Zapotoczna
Thoracic ultrasound for confirmation of central venous catheter placement
To evaluate the safety and utility of ultrasonography as a tool to confirm central venous catheter (CVC) position and to exclude insertion-related pneumothorax in place
Diagnosis and management of upper extremity deep vein thrombosis
They are increasing in frequency, largely due to the rising use of central venous catheters and implantable cardiac devices, and represent more than 10% of
Full text article describes a dramatic side effect from IV pethidine administration
We report an unusual and dramatic side effect from IV pethidine administration and its implications” Krishnan and Sultan (2014). Abstract: Pethidine is used in some
Point-of-care and clinical ultrasound guidelines in medicine
Since the last update of these guidelines in 2008, US use has expanded throughout clinical medicine and established itself as a standard in the clinical
What is the benefit of ultrasound screening pre vascular access device insertion?
Hence, plan to cannulate CV was abandoned, and USG-guided peripheral venous access with 22-gauge 80 mm polyethylene pediatric catheter (Leadercath, Vygon) was obtained in median
How to treat Deep Vein Thrombosis of the upper extremity – full text
Deep venous thrombosis (DVT) arises with an incidence of about 1 per 1000 persons per year; 4-10% of all DVTs are located in an upper
What should we expect from peripheral intravenous cannulation?
…this article will consider the risk of catheter-related bloodstream infections and needlestick injuries, national and international guidelines on infection prevention and safety in intravenous access…”
Evaluation of the impact of Vessel Health and Preservation Framework implementation
The Vessel Health and Preservation (VHP) framework was developed with the intention of providing frontline staff with a resource to assist in assessing and selecting
How to implement smart infusion pumps with dose-error reduction software
This article discuses the challenges and benefits of implementing DERS in clinical practice as experienced by three UK trusts” Heron (2017). Abstract: Intravenous (IV) drug