Intravenous news: “Officials at the National Heart, Lung, and Blood Institute (NHLBI) have halted a multicenter clinical trial ofÂ concentrated saline administered to patients who have experienced trauma and go into shock as a consequence of blood loss while they are en route to a hospital.
Last August, when the trial’s data and safety monitoring board found evidence that patients who received the concentrated saline were no more likely to survive than those who received a standard saline solution, it suspended enrollment in the trial. Patients in this study who received the concentrated solution were more likely to die in the emergency department or before reaching the hospital than were patients who received the standard saline solution. Both groups experienced a similar death rate during the 28-day period after treatment; however, deaths occurred later in the normal saline group” (Kuehn 2009).
Kuehn, B.M. (2009) Saline Trial Ended. JAMA. 301(20), p.2085.