The effect of blood coming into contact with silver-coated/impregnated needleless IV connectors


Intravenous literature: Chernecky, C.C., Waller, J.L. and Jarvis, W.R. (2013) In vitro study assessing the antibacterial activity of three silver-impregnated/coated mechanical valve needleless connectors after blood exposure. AJIC: American Journal of Infection Control. 41(3), p.278-28.


This in vitro study’s purpose was to assess antibacterial activity of 3 different connectors: V-Link (Baxter, Deerfield, IL), Ultrasite Ag (B. Braun, Bethlehem, PA), and MaxGuard (CareFusion, Ontario, CA), impregnated with silver nanoparticles after blood exposure. All 3 silver-coated/impregnated connectors grew Staphylococcus aureus and Staphylococcus epidermidis. Log reduction of bacteria was not significant (range, +0.19 to ?1.82). There was substantial bacterial recovery from all 3 connectors (mean ranges, 2.09 × 107 to 4.00 × 108) indicating that, once blood comes in contact with silver-coated/impregnated needleless connectors, their antibacterial activity is significantly reduced.

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