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Taurolidine-Citrate locks significantly reduced the rate of CLABSI, particularly Gram negative organisms without adverse events” Clark et al (2018).

Abstract:
This study describes a successful, targeted intervention in central venous access device routine care, to decrease central line associated bloodstream infection (CLABSI). Taurolidine-Citrate locks significantly reduced the rate of CLABSI, particularly Gram negative organisms without adverse events.

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Reference:

Clark, J., Graham, N., Kleidon, T. and Ullman, A. (2018) Taurolidine-Citrate Line Locks Prevent Recurrent Central Line Associated Bloodstream Infection in Pediatric Patients. The Pediatric Infectious Disease Journal. September 10th. [epub ahead of print].

doi: 10.1097/INF.0000000000002191.