Jasinsky, L.M. (2009) Occlusion Reduction and Heparin Elimination Trial Using an Antireflux Device on Peripheral and Central Venous Catheters. Journal of Infusion Nursing. 32(1), p.33-39.
Catheter occlusion and thrombosis are common problems associated with central venous catheters, peripherally inserted central catheters, and peripheral intravenous catheters. A prospective study was performed at a community hospital to determine whether an antireflux valve device would reduce the frequency of complications in these catheters and safely allow the elimination of heparin flushes for central venous catheters and peripherally inserted central catheters. The study compared complications with current intravenous practice to complication rates for the antireflux valve device. The study used evidence obtained during this trial to institute the best clinical practice.