Incidence of thrombosis in children with tunneled central venous access devices versus peripherally inserted central catheters (PICCs)

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#IVTEAM #Intravenous literature: Kanin, M. and Young, G. (2013) Incidence of thrombosis in children with tunneled central venous access devices versus peripherally inserted central catheters (PICCs). Thrombosis Research. August 30th. [epub ahead of print].

Abstract:

INTRODUCTION: The recent proliferation of deep vein thrombosis in children has been attributed to the increased use of central venous catheters, specifically tunneled lines and peripherally inserted central catheters. A formal comparison of the incidence rate for deep vein thrombosis between tunneled lines and peripherally inserted central catheters has not been undertaken.

METHODS: Children

RESULTS: Over the seven year study period there was an overall rate of 73 deep vein thromboses per 10,000 hospital discharges. Of the 6915 eligible subjects, 181 had a deep vein thrombosis for an overall incidence rate of 2.6%. There were 152 thrombi (2.6%) in subjects with peripherally inserted central catheters and 29 thrombi (3.1%) in subjects with tunneled lines [OR=.83 (0.55, 1.29), p=0.38].

CONCLUSION: Despite the relative ease and simplicity of use of peripherally inserted central catheters leading to a substantial rise in their use, this study demonstrates that such lines pose a substantial risk for venous thrombosis and no difference in incidence was detected between such lines and tunneled lines.

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