Etiology and epidemiology of catheter related bloodstream infections (CRBSI) in patients receiving home parenteral nutrition

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Intravenous literature: Nielsen, X.C., Chen, M., Hellesøe, A.M., Jeppesen, P.B., Gyldenlykke, J., Tvede, M. and Andersen, L.P. (2012) Etiology and epidemiology of catheter related bloodstream infections in patients receiving home parenteral nutrition in a gastromedical center at a tertiary hospital in denmark. The Open Microbiology Journal. Nov 30. [epub ahead of print].

Abstract:

We conducted a retrospective epidemiologic study of catheter related bloodstream infections (CRBSI) in patients receiving long-term home parenteral nutrition (HPN) from January 2002 to December 2005. Our results showed that coagulase negative staphylococci (CoNS) were the most prevalent pathogens (44.7% of all CRBSI episodes), followed by Enterobacteriaceae (33.2%). Prevalence for candidemia and Enterococcus bacteremia was relatively high (14.4% and 10.8%, respectively). Cefuroxime resistance was observed in 65.4% CoNS and 31.5% Enterobacteriaceae. Based on the results from the study, a new empiric antimicrobial treatment regiment was suggested.

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