#IVTEAM #Intravenous literature: “We retrospectively evaluated on a large cohort of patients the incidence of CVC-related early and late complications.” Morano et al (2014).
Morano, S.G., Coppola, L., Latagliata, R., Berneschi, P., Chistolini, A., Micozzi, A., Girmenia, C., Breccia, M., Brunetti, G., Massaro, F., Rosa, G., Guerrisi, P., Mandelli, F., Foà, R. and Alimena, G. (2014) Early and late complications related to central venous catheters in hematological malignancies: a retrospective analysis of 1102 patients. Mediterranean Journal of Hematology and Infectious Diseases. 6(1), p.e2014011.
Several severe complications may be associated with the use of central venous catheters (CVC). We retrospectively evaluated on a large cohort of patients the incidence of CVC-related early and late complications. From 7/99 to 12/2005, 1102 CVC have been implanted at our Institution in 881 patients with hematological malignancies (142,202 total day number of implanted CVC). Early mechanic complications were 79 (7.2% – 0.55/1,000 days/CVC). Thirty-nine episodes of early infective complications (<1 week from CVC implant) occurred (3.5% – 0.3/1000 days/CVC): furthermore, 187 episodes of CVC-related sepsis (17% – 1.3/1000 days/CVC) were recorded. There were 29 episodes (2.6%) of symptomatic CVC-related thrombotic complications, with a median interval from CVC implant of 60 days (range 7 – 395). The rate of CVC withdrawal due to CVC-related complications was 26%. The incidence of CVC-related complications in our series is in the range reported in the literature notwithstanding cytopenia often coexisting in hematological patients.
Other intravenous and vascular access resources that may be of interest (External links – IVTEAM has no responsibility for content).
- Guide for intravenous chemotherapy and associated vascular access devices from Macmillan.
- CancerUK IV chemotherapy information.