Comparison of chlorhexidine-gluconate and povidone-iodine for skin antisepsis at CVC sites

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#IVTEAM #Intravenous literature: “Chlorhexidine-gluconate ethanol was superior to povidone-iodine to reduce skin colonizers at CVC sites.” Yamamoto et al (2014).

Reference:

Yamamoto, N., Kimura, H., Misao, H., Matsumoto, H., Imafuku, Y., Watanabe, A., Mori, H., Yoshida, A., Miura, S., Abe, Y., Toba, M., Suzuki, H., Ogawa, K. and Kanemitsu, K. (2014) Efficacy of 1.0% chlorhexidine-gluconate ethanol compared with 10% povidone-iodine for long-term central venous catheter care in hematology departments: A prospective study. American Journal of Infection Control. March 18th. [epub ahead of print].

Abstract:

The efficacy of 1% chlorhexidine-gluconate ethanol and 10% povidone-iodine for skin antisepsis of central venous catheter (CVC) sites were compared among hematology patients. The CVC site colonization rates of those groups were 11.9% and 29.2%, respectively, and the catheter-associated blood stream infections were 0.75 and 3.62 per 1,000 catheter-days, respectively. One percent chlorhexidine-gluconate ethanol was superior to povidone-iodine to reduce skin colonizers at CVC sites even when catheters were used for long duration.

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