Cancer medication errors

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Seven percent of adults and 19 percent of children taking chemotherapy drugs in outpatient clinics or at home were given the wrong dose or experienced other mistakes involving their medications, according to a new study supported in part by HHS’ Agency for Healthcare Research and Quality through its Centers for Education and Research on Therapeutics program.

Researchers analyzed data on nearly 1,300 patient visits at three adult oncology outpatient clinics and 117 visits at one pediatric facility between September 1, 2005 and May 31, 2006. The study, “Medication Errors among Adults and Children with Cancer in the Outpatient Setting,” is in the January 1, 2009 issue of the Journal of Clinical Oncology .

Of the 7 percent of medication errors involving adults, 55 had the potential to harm the patient and 11 did cause harm. The errors included administration of incorrect medication doses due to confusion over conflicting orders – one written at the time of diagnosis and the other on the day of administration. Some consequences of errors included patients being over-hydrated prior to administration of chemotherapy and complaints of abdominal pain in patients taking narcotics without treatment for constipation. More than 50 percent of errors involving adults were in clinic administration, 28 percent in ordering of medications, and 7 percent in use of the drugs in patients’ homes.

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