Blood plasma update

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Intravenous literature: News-Medical.net report “Three years after the U.S. blood banking industry issued recommendations that discourage transfusing plasma from female donors because of a potential antibody reaction, Duke University Medical Center researchers discovered that female plasma actually may have advantages.

The Duke team conducted a retrospective study of Red Cross donor and hospital data from a period when female plasma wasn’t restricted. They examined heart surgery outcomes for lung problems, and prolonged length of hospital stay or death. Cardiac surgery patients use about one-fifth of all transfused blood products.

They found that patients receiving female-donor plasma did significantly better than similar patients receiving male-donor plasma.

“Our findings raise the possibility of unanticipated effects of restricting female donor plasma use,” said Mark Stafford-Smith, M.D., a Duke professor of anesthesiology and senior author of a study appearing in the Journal of Thoracic and Cardiovascular Surgery on Feb. 11.

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