Amiodarone and DEHP

April 17, 2008

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The team at Cardinal Health have just informed us that users of Amiodarone should consider administering Amiodarone through a specific aministration set. As Amiodarone may cause the plasticizers to leach into the fluid path.

Medicines.org.uk state that “The use of administration equipment or devices containing plasticizers such as DEHP (di-2-ethylhexyphthalate) in the presence of amiodarone may result in leaching out of DEHP. In order to minimise patient exposure to DEHP, the final amiodarone dilution for infusion should preferably be administered through non DEHP-containing sets.”